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Advancing veterinary knowledge in pet health is essential for veterinary professionals. Explore research articles dedicated to the latest studies and findings in the field. Stay informed about the most recent developments in pet health to provide the best possible care for your beloved animals.
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- Canine Mammary Carcinomas: A Comparative Analysis of Altered Gene Expression
Breast cancer represents the second most frequent neoplasm in humans and sexually intact female dogs after lung and skin cancers, respectively. Many similar features in human and dog cancers including... Read More
- Canine Histiocytic Malignancies Challenges and Opportunities
Canine histiocytic malignancies (HM) are aggressive tumors that occur with particularly high frequency in certain breeds including Bernese mountain dogs and flat-coated retrievers. Robust diagnosis of... Read More
- Understanding the Osteosarcoma Pathobiology: A Comparative Oncology Approach
Osteosarcoma is an aggressive primary bone tumor in humans and is among the most common cancer afflicting dogs. Despite surgical advancements and intensification of chemo- and targeted therapies, the ... Read More
- Therapeutic Innovations: Tyrosine Kinase Inhibitors in Cancer
Conventional cytotoxic chemotherapy involving DNA-interacting agents and indiscriminate cell death is no longer the future of cancer management. While chemotherapy is not likely to completely disappea... Read More
- An Alternative Vaccination Approach for The Prevention of Highly Pathogenic Avian Influenza Subtype H5N1 in The Red River Delta, Vietnam A Geospatial-Based Cost-Effectiveness Analysis
This study addresses the tradeoff between Vietnams national poultry vaccination program, which implemented an annual two-round HPAI H5N1 vaccination program for the entire geographical area of the Re... Read More
- Comparative Aspects of Canine Melanoma
Melanomas are malignant neoplasms originating from melanocytes. They occur in most animal species, but the dog is considered the best animal model for the disease. Melanomas in dogs are most frequentl... Read More
- Sentinel Animals in a One Health Approach to Harmful Cyanobacterial and Algal Blooms
People, domestic animals, and wildlife are all exposed to numerous environmental threats, including harmful algal blooms (HABs). However, because animals exhibit wide variations in diet, land use and ... Read More
- Establishment and Characterization of New Canine and Feline Osteosarcoma Primary Cell Lines
Osteosarcomas are the most abundant form of bone malignancies in multiple species. Canine osteosarcomas are considered a valuable model for human osteosarcomas because of their similar features. Felin... Read More
- Sequence Instability in the Proviral Long Terminal Repeat and gag Regions from Peripheral Blood and Tissue-Derived Leukocytes of FIV-Infected Cats during the Late Asymptomatic Phase
Feline immunodeficiency virus (FIV) infection results in viral persistence, a prolonged asymptomatic phase, and progressive immunopathology. During the asymptomatic phase, a cohort of experimentally F... Read More
- The Comparative Diagnostic Features of Canine and Human Lymphoma
The non-Hodgkin lymphomas (NHLs) are a heterogeneous family of lymphoid malignancies that are among the most common neoplasms of both dogs and humans. Owing to shared molecular, signaling, incidence, ... Read More
- Travelling between Two Worlds: Complement as a Gatekeeper for an Expanded Host Range of Lyme Disease Spirochetes
Evading innate immunity is a prerequisite for pathogenic microorganisms in order to survive in their respective hosts. Concerning Lyme disease spirochetes belonging to the Borrelia (B.) burgdorferi se... Read More
- Gliomatosis Cerebri in the Brain of a Cat
An eight-year-old, neutered, female, long-haired cat was presented with a three-week history of progressive lethargy, unlocalized pain in the cervical and lumbar spine, and unwillingness to move. An M... Read More
- Detection of Methicillin-Resistant Staphylococci Isolated from Food Producing Animals: A Public Health Implication
The emergence of antibiotic-resistant bacteria in food animals is a potential public health concern. Staphylococci are a significant opportunistic pathogen both in humans and dairy cattle. In the pres... Read More
- Anaplasma phagocytophilum Manipulates Host Cell Apoptosis by Different Mechanisms to Establish Infection
Anaplasma phagocytophilum is an emerging zoonotic pathogen that causes human and animal granulocytic anaplasmosis and tick-borne fever of ruminants. This obligate intracellular bacterium evolved to us... Read More
- Tick-Borne Relapsing Fever Spirochetes in the Americas
Relapsing fever spirochetes are tick- and louse-borne pathogens that primarily afflict those in impoverished countries. Historically the pathogens have had a significant impact on public health, yet c... Read More
- Cat Mammary Tumors: Genetic Models for the Human Counterpart
The records are not clear, but Man has been sheltering the cat inside his home for over 12,000 years. The close proximity of this companion animal, however, goes beyond sharing the same roof; it exten... Read More
- p16, pRb, and p53 in Feline Oral Squamous Cell Carcinoma
Feline oral squamous cell carcinoma (FOSCC) is a highly aggressive head and neck cancer in cats, but the molecular pathogenesis of this cancer is still uncertain. In this study, p16, p53, and pRb prot... Read More
- Pathogen and Host Response Dynamics in a Mouse Model of Borrelia hermsii Relapsing Fever
Most Borrelia species that cause tick-borne relapsing fever utilize rodents as their natural reservoirs, and for decades laboratory-bred rodents have served as informative experimental models for the ... Read More
- Ehrlichioses: An Important One Health Opportunity
Ehrlichioses are caused by obligately intracellular bacteria that are maintained subclinically in a persistently infected vertebrate host and a tick vector. The most severe life-threatening illnesses,... Read More
- Genomic Tools and Animal Health
Animals have been selected to improve their productivity in order to increase the profitability to the producer. In this scenario, not much attention was given to health traits. As a consequence of th... Read More